ZHUANZIZHONGGUOKEJIWANG：http://www.stdaily.com/index/kejixinwen/2020-10/16/content_1028723.shtml

       KEJIRIBAOJIZHE JUJIAN

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▲ZAIGUOJIYIXUEXUESHUQIKAN《LIUYEDAO》KANZAI

       GAIXIANGSUIJI、SHUANGMANG、ANWEIJIDUIZHAODEI/IIQISHIYAN，ZAIJIEDUAN1ZHONG，JIANG192MINGJIANKANGCHENGRENFENWEI18-59SUIZUHE≥60SUIZU，YIPINGGUDI、ZHONG、GAOJILIANGYIMIAO。MEIGEZUZHONGDECANYUZHEANZHAO3：1SUIJIFENPEI，FENBIEJIEZHONGYIMIAOHUOANWEIJI。ZAIDI2JIEDUANZHONG，JIANG448WEIJIANKANGCHENGREN（18-59SUI）FENPEIDAOSIGEZUZHONG，FENBIEZAIDI0TIANJIESHOUGAOJILIANGYIMIAO，HUOZAI0/14、0/21TIANHUO0/28TIANJIESHOUZHONGDENGJILIANGYIMIAO，ZHUYAOPINGGUANQUANXINGHENAISHOUXING，CIYAOJIEGUOSHIMIANYIYUANXING，PINGGUWEIZHENDUICHUANRANXINGSARS-CoV-2DEZHONGHEKANGTIFANYING。

       有效诱导产生中和抗体

       具有良好的免疫原性

       DUIHOUXUANYIMIAOYOUDAODEZHONGHEKANGTIJIYANGZHUANLVYANJIUJIEGUOXIANSHI，ⅠQILINCHUANGZHONG，JIANKANGCHENGRENZUZHONG，JIEZHONGDIJILIANGHEZHONGJILIANGDERENQUNXUEQINGZHUANHUALVZAIDI14TIANSHIJUNDADAO100％，JIEZHONGGAOJILIANGRENQUNDEXUEQINGZHUANHUALVZAIDI14TIANSHIDADAOLE96％。LAONIANZUZHONG，SUOYOURENQUNDEXUEQINGZHUANHUALVZAIDI28TIANJUNDADAO100％。SUOYOUZUZHONG，ZHONGHEKANGTICONGDI7TIANKAISHIXIANZHEZENGJIA，DI42TIANDADAOFENGZHI。GAOJILIANGZUYIMIAOYINQIDEZHONGHEKANGTIXIAOJIAMINGXIANGAOYUDIJILIANGZU，DANYUZHONGJILIANGZUWUMINGXIANCHAYI。CIWAI，YIMIAOYINQIDEZHONGHEKANGTIKEYIZHONGHEDUOZHONGBINGDUZHU，BAOKUODANGQIANDAIYOUTUBIANTIDEDALIUXINGZIRANBIANYIZHU（D614G）。ⅡQILINCHUANGJIEGUOXIANSHI，ZAID0/D14HED0/D21CHENGXUZHONG，ZHONGHEKANGTICONGDIERCIJIEZHONGHOUDEDI14TIANDAODI28TIANZENGJIA。D0/D21CHENGXUZHONGYIMIAOYINQIDEZHONGHEKANGTIDIDUXIANZHUGAOYUD0 /D14CHENGXUZHONGYIMIAOCHANSHENGDEZHONGHEKANGTIXIAOJIA。

       ZHEIYIJIEGUOBIAOMING，GAIYIMIAONENGZAIGAINIANLINGZURENQUNZHONGYOUXIAOYOUDAOCHANSHENGZHONGHEKANGTI，ZHONGHEKANGTISHUIPINGYEYUQITAYIMIAOYANJIUBAODAODESHUIPINGXIANGDANG，ZHENGSHILEGAIYIMIAOJUYOULIANGHAODEMIANYIYUANXING。

       在人体安全性好

       ZAIANQUANXINGFANGMIAN，LIANGZHENYIMIAOJIEZHONGHOUDEQIAN7TIANNEI，YOU42MING（ZHANBI30％）JIEZHONGZHECHUXIANBULIANGFANYING，ZHUYAOSHIZHUSHEBUWEITENGTONG，QICISHIFARE，DANJUNWEIQINGWEIHEZIXIANSHIDE，BUXURENHEZHILIAO。YANJIUZHONGWURENHEYUYIMIAOYOUGUANDEYANZHONGBULIANGSHIJIANFASHENG。QIZHONGCHUXIANZHUSHEBUWEITENGTONGDEYOU34REN（ZHANBI24％），CHUXIANFAREDEYOU5REN（5％）。

       BULIANGFANYINGFASHENGLVZAIYIMIAOZUHEANWEIJIZUJIANCHAYIWUTONGJIXUEYIYI，QIEDIYUMUQIANFABIAODEYIMIAOLINCHUANGYANJIUSUOBAODAODESHUIPING，SHUOMINGGAIMIEHUOYIMIAOZAIRENTIANQUANXINGHAO。

       Ⅲ期临床试验正在有序进行

       BEIJINGSHENGWUZHIPINYANJIUSUOYANFADEXINGUANMIEHUOYIMIAOYU4YUE27RIHUOGUOJIAYAOJIANJULINCHUANGSHIYANPIJIANBINGTONGBUQIDONGⅠ/ⅡQILINCHUANGSHIYAN。

       MUQIAN，ZHONGGUOSHENGWUSUOSHUBEIJINGSHENGWUZHIPINYANJIUSUOHEWUHANSHENGWUZHIPINYANJIUSUODELIANGGEXINGUANMIEHUOYIMIAOZHENGZAIALIANQIU、BALIN、AIJI、MOLUOGE、MILU、AGENTINGDENGGUOJIAYOUXUTUIJINⅢQILINCHUANGSHIYAN，YANGBENRENQUNXIANYIFUGAI125GEGUOJI，GEFANGMIANJINZHANJUNQUANQIULINGXIAN。